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KMID : 0191120140290121711
Journal of Korean Medical Science
2014 Volume.29 No. 12 p.1711 ~ p.1716
The Value of SPECT/CT in Localizing Pain Site and Prediction of Treatment Response in Patients with Chronic Low Back Pain
Lee In-Ki

Hendra Budiawan
Moon Jee-Youn
Cheon Gi-Jeong
Kim Yong-Chul
Paeng Jin-Chul
Kang Keon-Wook
Chung June-Key
Lee Dong-Soo
Abstract
In many circumstances, causing sites of low back pain (LBP) cannot be determined only by anatomical imaging. Combined functional and morphological imaging such as bone scan with single-photon emission computed tomography/computed tomography (SPECT/CT) may be helpful in identifying active lesions. The purpose of this study was to evaluate the usefulness of bone SPECT/CT in localizing the pain site and the treatment of chronic LBP. One hundred seventy-five patients suffering from chronic LBP who underwent SPECT/CT were included, retrospectively. All of the patients received multiple general treatments according to the symptoms, and some of them underwent additional target-specific treatment based on SPECT/CT. Numerical rating scale (NRS) pain score was used to assess the pain intensity. Of 175 patients, 127 showed good response to the given therapies, while the rest did not. Overall, 79.4% of patients with definite active lesions showed good response. Patients with mild active or no lesions on SPECT/CT had relatively lower response rate of 63.0%. Good response was observed by the treatment with the guidance of active lesions identified on SPECT/CT. SPECT/CT could be useful in identifying active lesions in patients with chronic LBP and guiding the clinicians to use adequate treatment.
KEYWORD
Low Back Pain, Tomography, Emission-Computed, Single-Photon, Tomography, X-Ray Computed, Pain Management, Technetium-99m (Tc-99m), Methylene Diphosphonate (MDP)
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